WrestleMania 42 Betting Odds Point to Huge Upset

WrestleMania 42 betting odds just took a surprising turn, and the biggest shock involves Brock Lesnar.

After previously being left off the board, BetOnline.AG has now released updated odds for the confirmed Brock Lesnar vs. Oba Femi match — and the numbers point to what could be one of the biggest upsets on the entire card.

According to the updated odds released March 21, 2026, Oba Femi is favored to defeat Lesnar, placing the rising powerhouse ahead of one of WWE’s most dominant names. That alone makes this one of the most talked-about betting developments tied to WrestleMania 42 so far.

Oba Femi is currently listed as a strong favorite at -350, while Brock Lesnar is the underdog at +225, signaling confidence that WWE could be preparing to elevate Femi in a major way. With Lesnar’s reputation for dominance and Femi’s rapid rise, this matchup now carries serious intrigue as fans speculate about whether WWE is planning a major breakout moment. Alongside the Lesnar vs. Femi update, other championship and marquee match odds remain active as the card continues to take shape.

Here are the full WrestleMania 42 betting odds as of March 21, 2026:

• WWE Women’s Championship
  • Rhea Ripley (-350) vs. Jade Cargill (+225)
• WWE Women’s World Championship
  • Liv Morgan (-250) vs. Stephanie Vaquer (+170)
• Undisputed WWE Championship Match
  • Randy Orton (-200) vs. Cody Rhodes (+150)
• Singles Match
  • Oba Femi (-350) vs. Brock Lesnar (+225)

With these numbers now in place, the Lesnar vs. Femi odds stand out as the most surprising development so far. Seeing Lesnar positioned as an underdog suggests that oddsmakers — and possibly internal expectations — view Femi as a serious threat heading into WrestleMania weekend.

Betting odds are always subject to change, especially as more wagers come in and WWE storylines develop closer to the event.  Fans who want to place their bets online can do so through BetOnline at this link.

Do you think Oba Femi defeating Brock Lesnar would be the biggest upset at WrestleMania 42, or do you expect Lesnar to prove the oddsmakers wrong? Let us know your thoughts and drop your feedback below.